Endocrine Abstracts

The aim of this study was to assess the physical well-being among women with thyrotoxicosis. It was important to investigate the relationship between thyrotoxicosis and muscle quantity and quality as being components of sarcopenia.Methods36 women over 40 years of age with thyrotoxicosis took part in this cross-sectional study. After excluding factors affecting physical performance and body composition 13 women remained (mean age 64...

Introduction: Grip strength is a valuable biomarker of an individual’s biological age. Weak grip strength is a key component of sarcopenia and frailty and is associated with subsequent poor health, disability and mortality. Skeletal muscle is one of the major target organs of thyroid hormones. Hyperthyroidism may affect skeletal muscles qualitatively and quantitatively, to the extent of developing muscle weakness and myopathy. There are few studies investigating grip stre...

Aim: The aim of this prospective study is to assess if there is any correlation between parathyroid hyperplasia detected by ultrasound and variables connected with secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD) stage 5, treated by dialysis and to determine the PTH level, above which the hyperplasia of parathyroid glands could be visualized.Methods: Thirty-one patients (14 men and 17 women) with CKD stage 5, treated by ...

Objectives: The aim of the study was to determine different types of thyroid nodules according to their elasticity and to evaluate the diagnostic accuracy of strain elastography in detection of thyroid cancer. 114 thyroid nodules in 84 patients were examined prospectively with conventional B-mode US, color Doppler, strain elastography (SE) and fine needle aspiration biopsy (FNAB). 72 nodules in 50 patients were submitted to surgery and histologically assessed. For final diagno...

Aim: The aim of this retrospective study is to assess the lipid disturbances in patients with autoimmune thyroiditis.Methods: 1380 patients with autoimmune thyroiditis, hospitalized in Endocrinology department of ‘St. Marina’ Hospital, Varna for the period of 2004–2015 year, participated in the study. After excluding conditions influencing lipid profile, 771 patients remained for analysis (36 men and 735 women, mean age 49.81±13.98 ye...

We report three generations of a family with MEN-2 A characterized by autosomal dominant inheritance and virtually 100% penetrance.The proband, 35-year-old man, was diagnosed and operated for pheochromocytoma of the right adrenal gland and medullary thyroid carcinoma (MTC) with lymph node metastasis in 2009. His mother turned out to be operated for bilateral pheochromocytoma at the age of 47 (in 1994) and had had a thyroid nodule. She died at the age of ...